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輸血醫(yī)學(xué)工程研究平臺(tái)

發(fā)布時(shí)間:2015-01-23 【字號(hào): 瀏覽次數(shù):
        輸血生物醫(yī)學(xué)工程平臺(tái)主要研究方向包括:血液代用品關(guān)鍵技術(shù)研究及新型攜氧代血漿研發(fā)等;血液保存質(zhì)量研究包括一氧化氮等對(duì)紅細(xì)胞變形性等功能的影響及高海拔地區(qū)血液保存質(zhì)量影響等;輸血材料包括生物材料的血液相容性評(píng)價(jià),聯(lián)袋型全血白細(xì)胞濾器、血小板濾器、血小板保存袋等輸血器具的研發(fā)。
        在血液代用品研究方向,團(tuán)隊(duì)近2年獲得四川省科技支撐計(jì)劃2項(xiàng),四川省技術(shù)創(chuàng)新工程專項(xiàng)1項(xiàng),四川省國(guó)際科技合作與交流研究計(jì)劃1項(xiàng),累計(jì)立項(xiàng)經(jīng)費(fèi)192萬(wàn)元;并與四川正康公司建立橫向聯(lián)合實(shí)驗(yàn)室“新一代多功能代血漿的研究開發(fā)”,與中山新行健醫(yī)藥科技有限公司合作開展“血紅蛋白類載氧藥物質(zhì)量標(biāo)準(zhǔn)研究”,累計(jì)立項(xiàng)經(jīng)費(fèi)160萬(wàn)元。發(fā)表SCI論文5篇,中文核心期刊4篇。在輸血材料方面,建立了較為完善的生物材料的血液相容性評(píng)價(jià)平臺(tái),獲得了國(guó)家自然科學(xué)青年基金及協(xié)和青年基金各1項(xiàng),承擔(dān)全國(guó)醫(yī)療器械生物學(xué)評(píng)價(jià)標(biāo)準(zhǔn)化技術(shù)委員會(huì)和全國(guó)輸液器具標(biāo)準(zhǔn)化技術(shù)委員會(huì)標(biāo)準(zhǔn)起草和驗(yàn)證工作2項(xiàng),并與國(guó)內(nèi)外多家企業(yè)聯(lián)合開展了包括醫(yī)療器械增塑劑溶出物研究,血小板保存功能研究,白細(xì)胞過濾研究等多項(xiàng)橫向項(xiàng)目,發(fā)表SCI論文2篇,中文核心期刊4篇,科研能力得到了國(guó)內(nèi)外同行的認(rèn)可。
       近兩年來,經(jīng)過全體成員的辛勤工作、共同努力,各方面都取得一定成果和積累,為團(tuán)隊(duì)今后的發(fā)展打下了堅(jiān)實(shí)的基礎(chǔ)。
In research direction of blood substitute, during the past two years, the team has obtained 2 Sichuan Science and Technology Support Programs, a Sichuan special technical innovation projects, a Sichuan Province international scientific and technological cooperation and exchange research program, and cumulative project funding was 1.92 million. In addition, the joint laboratory was established with Sichuan Zhengkang Corporation for “the study and development of new generation of multifunctional plasma substitute”, and the program “quality standard study of Hemoglobin oxygen-carrying drugs” was cooperated with Zhongshan Xinxingjian medical technology Ltd. and cumulative project funding was 1.6 million. The 5 SCI articles and 4 articles of Chinese core journals were published.
In research direction of transfusion materials, evaluation methods of blood compatibility of biomaterials were established. In 2014, a National Natural Science Foundation for the youth and a Chinese Academy of Medical Sciences and Peking Union Youth Fund was obtained, and two items of standard drafting and verification work were undertaken for Technical Committee of Standardization of Biological Evaluation on Medical Device and the National infusion equipments standard technology committee. Furthermore, we cooperated with Domestic and foreign enterprises for programs such as testing for plasticizer migration from kinds of medical devices, for the storage quality of platelet in platelet bags and quality of leukocyte filters etc. The 2 SCI articles and 4 articles of Chinese core journals were published, and the ability of research was recognized from Domestic and foreign counterparts.
Through hard work by all the team members in the past two years, each field has made some achievements and accumulation, which is a good foundation for the team to do better in the near future.

PI簡(jiǎn)介:

劉嘉馨
研究員,中國(guó)醫(yī)學(xué)科學(xué)院北京協(xié)和醫(yī)學(xué)院碩士生導(dǎo)師,全國(guó)醫(yī)療器械生物學(xué)評(píng)價(jià)標(biāo)準(zhǔn)化技術(shù)委員會(huì)委員,中國(guó)生物材料學(xué)會(huì)理事,中國(guó)醫(yī)學(xué)科學(xué)院學(xué)術(shù)委員會(huì)委員,中國(guó)醫(yī)療保健國(guó)際交流促進(jìn)會(huì)醫(yī)療保健器械行業(yè)專業(yè)委員會(huì)副主任委員,中國(guó)微循環(huán)學(xué)會(huì)血液流變委專業(yè)員會(huì)委員,四川省生物醫(yī)學(xué)工程學(xué)會(huì)常務(wù)理事,四川省輸血協(xié)會(huì)專家委員會(huì)委員,中國(guó)輸血雜志、國(guó)際輸血及血液學(xué)雜志編委。1985年畢業(yè)于上海復(fù)旦大學(xué)化學(xué)系,1988年畢業(yè)于成都科技大學(xué)高分子材料系獲碩士學(xué)位。近年承擔(dān)國(guó)家高技術(shù)研究發(fā)展計(jì)劃(863計(jì)劃)子課題、國(guó)家科技支撐計(jì)劃項(xiàng)目、四川省科技支撐計(jì)劃項(xiàng)目等各類科研項(xiàng)目20余項(xiàng),獲得各類科研經(jīng)費(fèi)500余萬(wàn)元,發(fā)表SCI論文、中文核心期刊論文40余篇。
Prof. Jiaxin Liu
Committee member of Technical Committee of Standardization of Biological Evaluation on Medical Device, syndic of Chinese Society for Biomaterials, committee member of Academic Committee of  Chinese Academy of Medical Sciences, Vice Chairman of China International Exchange and Promotive Association For Medical and Health Care, Committee member of Chinese Microcirculation Society of Hemorheology Professional Committee, Standing director of Sichuan Biomedical Engineering Society, Committee member of Sichuan Blood Transfusion Professional Committee, editorial board member of “Chinese Journal of Blood Transfusion” and “International Journal of Blood Transfusion and Hematology”.
Prof. Jiaxin Liu was graduated from Chemistry Department of Fudan University, and post-graduated from Polymer Materials Department of Chengdu University of Science and Technology. In recent years, J.X. Liu has been responsible for appropriate twenty important national projects, including branch project of National High-tech R&D Program (863 Program), National Key Technology Support Program and Sichuan Key Technology Support Program. Additionally, J.X. Liu leads his team to achieve about five million RMB technology research funding, and publish approximately forty SCI articles and Chinese Core Journals.
Transfusion biomedical engineering research team was established in April 2013, and it belonged to level A team of institute of blood transfusion. The primary research fields of this team includes critical technologies of blood substitute and the new generation of oxygen-carrying plasma; blood storage quality research such as the influence of nitric oxide on red blood cell deformability and the storage quality of high altitude blood; blood transfusion materials research such as evaluation of blood compatibility of biomaterials and research and development of transfusion equipments including Alliance bag type of leukocyte filters for whole blood, filters for platelet and platelet storage bags.
Tel:0086-28-61648520        E-mail: jxliu8122@vip.sina.com
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